SCIENCE A NEW G OL DEN AGE A REPORT TO THE PRESIDENT BY MICHAEL KRATSIOS DIRECTOR OF THE WHITE HOUSE OFFICE OF SCIENCE AND TECHNOLOGY POLICY JULY 2026 i “The American story is one of boundless creativity and bold ambition, driven by an indomitable pioneering spirit that propels exploration and discovery. It is this spirit that illuminated the world with Edison’s lightbulb, carried the Wright brothers into the skies, and sent Armstrong to the moon. Today, a new frontier of scientific discovery lies before us.” President Donald J. Trump January 23, 2025 SCIENCE: A NEW GOLDEN AGE ii letter of transmittal  v president trump’s letter  viii summary of the report  x chapter i introduction Scientific Progress Remains Essential  1 As the Source of Our Triumphs  2 The Landscape Is Changing  3 New Frontiers and New Approaches  4 Growing Private Sector R&D  5 The Linear Model No Longer Holds  7 Our Researchers Face Mounting Challenges  8 A Time of Urgent Scientific Need  8 Regaining Leadership  10 The President’s Charge  11 chapter ii revitalizing america’s science and technology enterprise The Scientific Machine Is Getting Bogged Down  13 Slowed by Growing Frictions  15 The Incumbency Tax  15 Weakened Meritocracy  17 Misaligned Incentives  17 The Reproducibility Crisis  18 A Lack of Accountability  19 A Better Path Forward  20 Adapting to the Changing Nature of Science  22 Novel Performers  24 New Mechanisms  26 Better Grantmaking  27 Prize Challenges  28 Future Ideas  29 A Portfolio-Based Approach  30 Driving Constant Innovation  31 Table of Contents iii chapter iii securing u.s. dominance in critical and emerging technologies We Must Choose Our Technological Future  33 Failure of the Passive Model  34 Choosing to Lead  35 Fighting in Our Own Arena  35 Unleashing Innovation  36 The Freedom to Build  37 Places to Test  38 Opening America’s Laboratories  40 Tapping Our Private Sector  41 Closer Partnerships  42 Marshaling Grand Efforts  43 Pre-Competitive Consortia  44 Our National Character  45 chapter iv ensuring that science and technology better the lives of all americans The Marriage of Science and Craft  47 Our Manufacturing Base  48 Vast Potential Remains Untapped  49 Our Educational System Tilted the Scales  50 We Must Restructure Science as a Broader Endeavor  51 Expanding Participation  52 Integrated Models of Training  53 New Paths for Translation  54 Making Progress Available to All  55 Table of Contents iv chapter v a new golden age The Age of Intelligence  57 Adapting Our Institutions  59 Building the Infrastructure  61 The Genesis Mission  62 Gold Standard Science  64 Ideas on the Horizon  66 Rethinking Scientific Publication  67 New Forms of Collaboration and Credit  68 As We May Build  70 end notes  73 annex white house fiscal year 2028 administration research and development budget priorities memorandum  85 FY 2028 R&D Priority Areas  87 R&D Priority Practices  95 Implementation  104 Table of Contents v Dear Mr. President: Eighty-one years ago, President Franklin D. Roosevelt wrote a letter to Vannevar Bush, tasking him with reorganizing America’s scientific enterprise after World War II. Bush’s response was a report, titled Science: The Endless Frontier. It estab­ lished the Federal Government’s role in supporting basic science, led to the cre­ ation of the National Science Foundation, and shaped our nation’s science and technology strategy for decades afterward. That report was foundational to the American Century and to the technological world in which we live today. Now, as we celebrate the United States’ 250th anniversary, we have the responsibility to renew our foundations once more. Never have science and tech­ nology been more central to our nation’s security and prosperity, and, although America continues to set the pace of scientific progress, global competitors are racing to challenge our leadership. This historical moment demands that we modernize our institutions to match the achievements of our past and the ambi­ tions of our future. In your letter of March 26, 2025, on the occasion of my Senate confirmation as Director of the Office of Science and Technology Policy, you challenged me to reexamine America’s research and development ecosystem in light of changes brought on by the 21st century. The report I present here diagnoses the obstacles American researchers face today, and the ways our scientific enterprise has fundamentally transformed since its basic organization was established in 1945. Though our investments in research have grown, scientific productivity has slowed. We have become dependent on a narrow set of legacy institutions. Our incentive structures reward conformity over bold inquiry. And the capacity that once turned American discoveries into Ameri­ can strength has eroded, undermined by decades of industrial offshoring. To address these and related challenges, this report puts forward recommen­ dations for the entire scientific and technological ecosystem, across government, academia, philanthropy, and industry. Underlying all of these recommendations is Letter of Transmittal July 21, 2026 EXECUTIVE OFFICE OF THE PRESIDENT OFFICE OF SCIENCE AND TECHNOLOGY POLICY WASHINGTON, D.C. 20502