Title: "multivitamin" "biological aging" COSMOS trial at DuckDuckGo

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## [COSMOS Trial Results Show Daily Multivitamin Use May Slow Biological Aging](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.massgeneralbrigham.org%2Fen%2Fabout%2Fnewsroom%2Fpress%2Dreleases%2Fdaily%2Dmultivitamin%2Duse%2Dmay%2Dslow%2Daging&rut=c015bd76cdaaf0fde1c6f57057ca4908f4fe4bbb8b5609fd8514f3acb2de4588)

[![Image 1](https://external-content.duckduckgo.com/ip3/www.massgeneralbrigham.org.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.massgeneralbrigham.org%2Fen%2Fabout%2Fnewsroom%2Fpress%2Dreleases%2Fdaily%2Dmultivitamin%2Duse%2Dmay%2Dslow%2Daging&rut=c015bd76cdaaf0fde1c6f57057ca4908f4fe4bbb8b5609fd8514f3acb2de4588)[www.massgeneralbrigham.org/en/about/newsroom/press-releases/daily-multivitamin-use-may-slow-aging](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.massgeneralbrigham.org%2Fen%2Fabout%2Fnewsroom%2Fpress%2Dreleases%2Fdaily%2Dmultivitamin%2Duse%2Dmay%2Dslow%2Daging&rut=c015bd76cdaaf0fde1c6f57057ca4908f4fe4bbb8b5609fd8514f3acb2de4588) 2026-03-09T00:00:00.0000000

[The **COSMOS** team plans to investigate how the effects of a daily **multivitamin** on **biological aging** may extend to different outcomes they have seen evidence of benefits for, such as improvements in cognition and reductions in cancer and cataracts.](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.massgeneralbrigham.org%2Fen%2Fabout%2Fnewsroom%2Fpress%2Dreleases%2Fdaily%2Dmultivitamin%2Duse%2Dmay%2Dslow%2Daging&rut=c015bd76cdaaf0fde1c6f57057ca4908f4fe4bbb8b5609fd8514f3acb2de4588)

## [Daily multivitamin delays biological aging by up to 5 months, trial finds](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2Fdaily%2Dmultivitamin%2Ddelays%2Dbiological%2Daging%2Dmonths%2Dcosmos%2Dtrial&rut=dd0843f8cb1844635f8ced734c2547f2310b2e9606bd7360f492219ee7c206f6)

[![Image 2](https://external-content.duckduckgo.com/ip3/www.medicalnewstoday.com.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2Fdaily%2Dmultivitamin%2Ddelays%2Dbiological%2Daging%2Dmonths%2Dcosmos%2Dtrial&rut=dd0843f8cb1844635f8ced734c2547f2310b2e9606bd7360f492219ee7c206f6)[www.medicalnewstoday.com/articles/daily-multivitamin-delays-biological-aging-months-cosmos-trial](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2Fdaily%2Dmultivitamin%2Ddelays%2Dbiological%2Daging%2Dmonths%2Dcosmos%2Dtrial&rut=dd0843f8cb1844635f8ced734c2547f2310b2e9606bd7360f492219ee7c206f6) 2026-03-10T00:00:00.0000000

[The **COSMOS****trial** found that a daily **multivitamin** delayed **biological aging** by 2.7 to 5.1 months, and that this effect was more apparent in older adults who are already experiencing accelerated aging.](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2Fdaily%2Dmultivitamin%2Ddelays%2Dbiological%2Daging%2Dmonths%2Dcosmos%2Dtrial&rut=dd0843f8cb1844635f8ced734c2547f2310b2e9606bd7360f492219ee7c206f6)

## [Effects of daily multivitamin-multimineral and cocoa extract ...](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41591%2D026%2D04239%2D3&rut=4c88447684b80e25228fdffcf5fe4791ce82ce42b1994657a6e25dbc0a0924b4)

[![Image 3](https://external-content.duckduckgo.com/ip3/www.nature.com.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41591%2D026%2D04239%2D3&rut=4c88447684b80e25228fdffcf5fe4791ce82ce42b1994657a6e25dbc0a0924b4)[www.nature.com/articles/s41591-026-04239-3](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41591%2D026%2D04239%2D3&rut=4c88447684b80e25228fdffcf5fe4791ce82ce42b1994657a6e25dbc0a0924b4) 2026-03-09T00:00:00.0000000

[In a prespecified ancillary analysis of the **COSMOS** randomized **trial**, supplementation with daily **multivitamins**, but not with cocoa extract, over the course of 2 years decreased **biological aging**, as ...](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41591%2D026%2D04239%2D3&rut=4c88447684b80e25228fdffcf5fe4791ce82ce42b1994657a6e25dbc0a0924b4)

## [Daily multivitamin may slow biological aging — Harvard Gazette](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fnews.harvard.edu%2Fgazette%2Fstory%2F2026%2F03%2Fdaily%2Dmultivitamin%2Dmay%2Dslow%2Dbiological%2Daging%2F&rut=20736ffbc4b147b75f6fe252138cb4fa2126d479e9c29b0c2fcb8b9a7a9eba1d)

[![Image 4](https://external-content.duckduckgo.com/ip3/news.harvard.edu.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fnews.harvard.edu%2Fgazette%2Fstory%2F2026%2F03%2Fdaily%2Dmultivitamin%2Dmay%2Dslow%2Dbiological%2Daging%2F&rut=20736ffbc4b147b75f6fe252138cb4fa2126d479e9c29b0c2fcb8b9a7a9eba1d)[news.harvard.edu/gazette/story/2026/03/daily-multivitamin-may-slow-biological-aging/](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fnews.harvard.edu%2Fgazette%2Fstory%2F2026%2F03%2Fdaily%2Dmultivitamin%2Dmay%2Dslow%2Dbiological%2Daging%2F&rut=20736ffbc4b147b75f6fe252138cb4fa2126d479e9c29b0c2fcb8b9a7a9eba1d) 2026-03-09T00:00:00.0000000

[How quickly our bodies age on a cellular level — our "biological age" — can differ from how old we actually are in years. Using data from a large randomized clinical **trial** of older adults, researchers from Harvard and Mass General Brigham evaluated the effects of taking a daily **multivitamin** over the course of two years on five measures of **biological aging** and found a slowing equivalent ...](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fnews.harvard.edu%2Fgazette%2Fstory%2F2026%2F03%2Fdaily%2Dmultivitamin%2Dmay%2Dslow%2Dbiological%2Daging%2F&rut=20736ffbc4b147b75f6fe252138cb4fa2126d479e9c29b0c2fcb8b9a7a9eba1d)

## [COSMOS Trial: Daily Multivitamins Significantly Slow Biological Aging ...](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fgetbiobrief.com%2Fstory%2Fcosmos%2Dtrial%2Dmultivitamins%2Dbiological%2Daging&rut=7796a4b55af961290b2f3ffe7ef24dd0f4271a516be99e44a398fb06f9a0c4e4)

[![Image 5](https://external-content.duckduckgo.com/ip3/getbiobrief.com.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fgetbiobrief.com%2Fstory%2Fcosmos%2Dtrial%2Dmultivitamins%2Dbiological%2Daging&rut=7796a4b55af961290b2f3ffe7ef24dd0f4271a516be99e44a398fb06f9a0c4e4)[getbiobrief.com/story/cosmos-trial-multivitamins-biological-aging](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fgetbiobrief.com%2Fstory%2Fcosmos%2Dtrial%2Dmultivitamins%2Dbiological%2Daging&rut=7796a4b55af961290b2f3ffe7ef24dd0f4271a516be99e44a398fb06f9a0c4e4) 2026-03-09T00:00:00.0000000

[Key Takeaways A prespecified analysis of the large-scale **COSMOS****trial** has found that daily **multivitamin**-multimineral supplementation significantly slows markers of **biological aging** in older adults. The study provides robust clinical evidence that standard nutritional interventions can influence cellular longevity and epigenetic health beyond simple deficiency prevention.](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fgetbiobrief.com%2Fstory%2Fcosmos%2Dtrial%2Dmultivitamins%2Dbiological%2Daging&rut=7796a4b55af961290b2f3ffe7ef24dd0f4271a516be99e44a398fb06f9a0c4e4)

## [Effects of daily multivitamin-multimineral and cocoa extract ... - PubMed](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F41803341%2F&rut=3673d043f9db3fa72955979b8931f7953028a2874dfdba288ab1b68d62181be4)

[![Image 6](https://external-content.duckduckgo.com/ip3/pubmed.ncbi.nlm.nih.gov.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F41803341%2F&rut=3673d043f9db3fa72955979b8931f7953028a2874dfdba288ab1b68d62181be4)[pubmed.ncbi.nlm.nih.gov/41803341/](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F41803341%2F&rut=3673d043f9db3fa72955979b8931f7953028a2874dfdba288ab1b68d62181be4)

[Large-scale randomized **trials** have found that **multivitamin**-multimineral (MVM) supplements and cocoa flavanols may benefit several age-related chronic conditions among older adults, but it remains unclear whether these two supplements directly slow the **biological aging** process. This prespecified anci …](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F41803341%2F&rut=3673d043f9db3fa72955979b8931f7953028a2874dfdba288ab1b68d62181be4)

## [COSMOS trial results show daily multivitamin use may slow biological aging](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.eurekalert.org%2Fnews%2Dreleases%2F1118757&rut=927ab8539f4b22e17f0b1dd3e7c4aee37235ddfa6d6e3afa85f9d136a2fdeb28)

[![Image 7](https://external-content.duckduckgo.com/ip3/www.eurekalert.org.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.eurekalert.org%2Fnews%2Dreleases%2F1118757&rut=927ab8539f4b22e17f0b1dd3e7c4aee37235ddfa6d6e3afa85f9d136a2fdeb28)[www.eurekalert.org/news-releases/1118757](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.eurekalert.org%2Fnews%2Dreleases%2F1118757&rut=927ab8539f4b22e17f0b1dd3e7c4aee37235ddfa6d6e3afa85f9d136a2fdeb28) 2026-03-09T00:00:00.0000000

[The **COSMOS** team plans to investigate how the effects of a daily **multivitamin** on **biological aging** may extend to different outcomes they have seen evidence of benefits for, such as improvements in ...](https://duckduckgo.com/l/?uddg=https%3A%2F%2Fwww.eurekalert.org%2Fnews%2Dreleases%2F1118757&rut=927ab8539f4b22e17f0b1dd3e7c4aee37235ddfa6d6e3afa85f9d136a2fdeb28)

## [Effects of daily multivitamin-multimineral supplementation on ...](https://duckduckgo.com/l/?uddg=https%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11357%2D026%2D02197%2D9&rut=648460cec5f807349205362c957192a18b05b66b65bd208c92f2550b3d8a07a6)

[![Image 8](https://external-content.duckduckgo.com/ip3/link.springer.com.ico)](https://duckduckgo.com/l/?uddg=https%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11357%2D026%2D02197%2D9&rut=648460cec5f807349205362c957192a18b05b66b65bd208c92f2550b3d8a07a6)[link.springer.com/article/10.1007/s11357-026-02197-9](https://duckduckgo.com/l/?uddg=https%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11357%2D026%2D02197%2D9&rut=648460cec5f807349205362c957192a18b05b66b65bd208c92f2550b3d8a07a6) 2026-03-30T00:00:00.0000000

[Despite widespread use in the USA, little is known about the impact of **multivitamin**-multimineral (MVM) supplementation on metabolomic profiles and how this may translate to **biological aging** and long-term risk of age-related chronic diseases. The COcoa Supplement and **Multivitamin** Outcomes Study (**COSMOS**) is a 2 × 2 factorial, placebo-controlled, double-blinded, randomized clinical **trial** testing ...](https://duckduckgo.com/l/?uddg=https%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11357%2D026%2D02197%2D9&rut=648460cec5f807349205362c957192a18b05b66b65bd208c92f2550b3d8a07a6)

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