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  "europepmc_afa_cd34": {
    "url": "https://europepmc.org/article/MED/17765649",
    "status": 200,
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    "title": "Europe PMC",
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  "fda_regen_consumer": {
    "url": "https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies",
    "status": 200,
    "final": "https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies",
    "title": "Important Patient and Consumer Information About Regenerative Medicine Therapies | FDA",
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        "stem cells",
        "s. These products require FDA licensure/approval to be marketed to consumers. Before approval, these products require FDA oversight in a clinical trial. These unapproved products whether recovered from your own body or another person’s body, include stem cells, stromal vascular fraction (fat-derived cells), umbilical cord blood and/or cord blood stem cells 1 , amniotic fluid, Wharton’s jelly, ortho-biologics, and exosomes . FDA has received reports of blindness, tumor formation, infections, and more, detailed below, due to the use of these unapproved products. If you are being offered any of these products outside of a clinical trial for which FDA has oversight, please contact FDA at ocod@fda.hhs.gov . Additionally, contact FDA if you are considering treatment with any of these products and have questions, or if you have been treated with these products and wish to report any adverse effects or file a complaint. We take these reports seriously and want to hear from you. If you were hurt or had a bad side effect following treatment with a regenerative medicine product, or a similar product, we also encourage you to report it to the F"
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        "FDA",
        "Therapies\", \"description\": \"There continues to be broad marketing of unapproved products considered regenerative medicine therapies that are intended for the treatment or cure of a wide range of diseases or medical conditions. These products require FDA licensure/approval to be marketed to consumers.\", \"image\": { \"@type\": \"ImageObject\", \"representativeOfPage\": \"True\", \"url\": \"https://www.fda.gov/files/StemCells.jpg\" }, \"datePublished\": \"Mon, 04/08/2024 - 13:51\", \"dateModified\": \"Mon, 04/08/2024 - 13:00\", \"author\": { \"@type\": \"Organization\", \"name\": \"Center for Biologics Evaluation and Research\" }, \"publisher\": { \"@type\": \"Organization\", \"name\": \"FDA\" } } ] } Important Patient and Consumer Information About Regenerative Medicine Therapies | FDA window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag(\"js\", new Date());gtag(\"set\", \"developer_id.dMDhkMT\", true);gtag(\"config\", \"G-273DTKB5QW\", {\"groups\":\"default\",\"page_placeholder\":\"PLACEHOLDER_page_location\",\"allow_ad_personalization_signals\":false}); Skip to main content Skip to FDA Search Skip to in this section menu Skip to footer links An official we"
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      [
        "not approved",
        " stem cells (also known as hematopoietic progenitor cells) that are derived from umbilical cord blood. These products are approved for use in patients with disorders that affect the production of blood (i.e., the “hematopoietic” system) but they are not approved for other uses. Content current as of: 04/08/2024 Regulated Product(s) Biologics Feedback FDA Archive About FDA Accessibility Visitor Information Website Policies / Privacy No FEAR Act Vulnerability Disclosure Policy FOIA HHS.gov USA.gov Contact FDA Follow FDA on Facebook Follow FDA on X Follow FDA on Instagram Follow FDA on LinkedIn View FDA videos on YouTube Subscribe to FDA RSS feeds Contact Number 1-888-INFO-FDA (1-888-463-6332) Back to Top {\"path\":{\"baseUrl\":\"\\/\",\"pathPrefix\":\"\",\"currentPath\":\"node\\/409845\",\"currentPathIsAdmin\":false,\"isFront\":false,\"currentLanguage\":\"en\"},\"pluralDelimiter\":\"\\u0003\",\"suppressDeprecationErrors\":true,\"fda_ckeditor_enhancements\":{\"basePath\":\"modules\\/custom\\/fda_ckeditor_enhancements\"},\"google_analytics\":{\"account\":\"G-273DTKB5QW\",\"trackOutbound\":true,\"trackMailto\":true,\"trackTel\":true,\"trackDownload\":true,\"trackDownloadExtensions\":\"7z|aac|"
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  "fda_regen_alert": {
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    "status": 200,
    "final": "https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/consumer-alert-regenerative-medicine-products-including-stem-cells-and-exosomes",
    "title": "Consumer Alert on Regenerative Medicine Products Including Stem Cells and Exosomes | FDA",
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        "a.org\", \"@graph\": [ { \"@type\": \"Article\", \"headline\": \"Consumer Alert on Regenerative Medicine Products Including Stem Cells and Exosomes\", \"name\": \"Consumer Alert on Regenerative Medicine Products Including Stem Cells and Exosomes\", \"description\": \"FDA encourages patients to report Adverse Events Related to Stem Cells, Exosomes, or Other Products Marketed as Regenerative Medicine Products.\", \"datePublished\": \"Tue, 04/09/2024 - 10:13\", \"dateModified\": \"Tue, 04/09/2024 - 10:12\", \"author\": { \"@type\": \"Organization\", \"name\": \"Center for Biologics Evaluation and Research\" }, \"publisher\": { \"@type\": \"Organization\", \"name\": \"FDA\" } } ] } Consumer Alert on Regenerative Medicine Products Including Stem Cells and Exosomes | FDA window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag(\"js\", new Date());gtag(\"set\", \"developer_id.dMDhkMT\", true);gtag(\"config\", \"G-273DTKB5QW\", {\"groups\":\"default\",\"page_placeholder\":\"PLACEHOLDER_page_location\",\"allow_ad_personalization_signals\":false}); Skip to main content Skip to FDA Search Skip to in this section menu Skip to footer links An official website of the United State"
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        "not approved",
        " stem cells (also known as hematopoietic progenitor cells) that are derived from umbilical cord blood. These products are approved for use in patients with disorders that affect the production of blood (i.e., the “hematopoietic” system) but they are not approved for other uses. Exosome products are also regulated by FDA. As a general matter, exosome products intended to treat diseases or conditions in humans require FDA approval. There are currently no FDA-approved exosome products. Anyone considering the use of anything purported to be a regenerative medicine product, including stem cell products, exosome products, or other widely promoted products such as products derived from adipose tissue (this product is also known as stromal vascular fraction), human umbilical cord blood, Wharton’s Jelly, or amniotic fluid should know: None of these products have been approved for the treatment or prevention of COVID-19, acute respiratory distress syndrome (ARDS), or any other complication related to COVID-19. None of these products have been approved for the treatment of any orthopedic condition, such as osteoarthritis, tendonitis, disc dise"
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        "bone marrow",
        "epair. For what diseases or conditions are stem cell treatments well established? The range of diseases for which there are proven treatments based on stem cells is still extremely small. Disorders of the blood and immune system and acquired loss of bone marrow function can, in some cases, be treated effectively with blood stem cell transplantation. Doctors have been transferring blood stem cells by bone marrow transplant for more than 50 years, and advanced techniques for collecting blood stem cells are now used clinically. Umbilical cord blood, like bone marrow, is often collected as a source of blood stem cells and is being used experimentally as an alternative to bone marrow in transplantation. Other tissue-specific stem cells may also play a role in tissue transplants that have been performed for several years. For tissues and organs such as skin and cornea, stem cells contained in these tissues contribute to longterm regeneration. Other stem cell treatments are still experimental. This means that it has not yet been shown that this treatment is safe or that it will work. What are some of the special considerations for stem cel"
      ],
      [
        "FDA",
        "dually increased and the new intervention is compared against existing treatments. Once safety and effectiveness is demonstrated through this formal process, a national or regional regulatory agency, for example, the US Food and Drug Administration (FDA) or the European Medicines Agency (EMA), will approve the use of the treatment for particular diseases or conditions. What are the differences between an approved clinical treatment and an experimental intervention? An approved clinical treatment is a medical practice that has been shown through a formal process of clinical trials to be reasonably safe and effective for treating a particular disease or condition. Normally, such treatments will be approved by a national or regional regulatory agency, for example, the US Food and Drug Administration (FDA) or the European Medicines Agency (EMA). An experimental intervention is new, untested, or different from the usual medical treatment. It has not yet been proven that it is safe or that it will work in treating the particular disease. What is a clinical trial? A clinical trial is a research study designed to answer specific questions a"
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        "cell therapy",
        "at are found in various tissues in our bodies. Recently, cells with properties similar to embryonic stem cells, referred to as induced pluripotent stem cells (iPS cells), have been engineered from specialized cells such as skin cells. What is a stem cell therapy? A stem cell therapy is a treatment that uses stem cells, or cells that come from stem cells, to replace or to repair a patient’s cells or tissues that are damaged. The stem cells might be put into the blood, or transplanted into the damaged tissue directly, or even recruited from the patient’s own tissues for self-repair. For what diseases or conditions are stem cell treatments well established? The range of diseases for which there are proven treatments based on stem cells is still extremely small. Disorders of the blood and immune system and acquired loss of bone marrow function can, in some cases, be treated effectively with blood stem cell transplantation. Doctors have been transferring blood stem cells by bone marrow transplant for more than 50 years, and advanced techniques for collecting blood stem cells are now used clinically. Umbilical cord blood, like bone marrow"
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  "health_canada_warning": {
    "url": "https://recalls-rappels.canada.ca/en/alert-recall/health-canada-advising-canadians-about-potential-health-risks-associated-unauthorized",
    "status": 200,
    "final": "https://recalls-rappels.canada.ca/en/alert-recall/health-canada-advising-canadians-about-potential-health-risks-associated-unauthorized",
    "title": "Health Canada is advising Canadians about the potential health risks associated with unauthorized cell therapy treatments such as stem cell therapy - Canada.ca",
    "snippets": [
      [
        "stem cells",
        "for-profit clinics offering a process called “autologous cell therapies,” which may also be offered to patients under other names, such as “bone marrow aspirate concentration (BMAC) injections,” “stromal vascular fraction (SVF),” or “adipose-derived stem cells.” This process uses people’s own cells to treat their health conditions. These therapies involve removing some cells from the patient, manipulating or processing those cells, and then reintroducing them back into the patient. The intent is to treat or prevent a disease, disorder or medical condition, such as pain or osteoarthritis. Because autologous cell therapy uses a patient’s own cells, practitioners may suggest that these treatments are safe; however, they have not been proven to be safe or effective. The Department has taken action against multiple clinics that offer cell therapies. If any clinic is found to be offering unauthorized cell therapies to Canadians, Health Canada will follow up and take appropriate and timely action. To verify that treatments are authorized, Canadians should refer to Health Canada’s Drug Product Database and Clinical Trials Database to confir"
      ],
      [
        "bone marrow",
        "actitioner is conducting a clinical trial authorized by Health Canada. One current trend in cell therapies is for-profit clinics offering a process called “autologous cell therapies,” which may also be offered to patients under other names, such as “bone marrow aspirate concentration (BMAC) injections,” “stromal vascular fraction (SVF),” or “adipose-derived stem cells.” This process uses people’s own cells to treat their health conditions. These therapies involve removing some cells from the patient, manipulating or processing those cells, and then reintroducing them back into the patient. The intent is to treat or prevent a disease, disorder or medical condition, such as pain or osteoarthritis. Because autologous cell therapy uses a patient’s own cells, practitioners may suggest that these treatments are safe; however, they have not been proven to be safe or effective. The Department has taken action against multiple clinics that offer cell therapies. If any clinic is found to be offering unauthorized cell therapies to Canadians, Health Canada will follow up and take appropriate and timely action. To verify that treatments are auth"
      ],
      [
        "patient",
        "ies OTTAWA – Health Canada is advising Canadians that some clinics and health care practitioners are offering unauthorized cell therapies, such as stem cell therapy, suggesting that these treatments are safe, and are making unproven health claims to patients. These actions may pose risks to Canadians. Unauthorized treatments have not been proven to be safe or effective and may cause life threatening or life altering risks, such as serious infections. That is why Health Canada published a position paper to clarify the regulatory status of these products. All cell therapies are considered drugs under the Food and Drugs Act . This means that they must be authorized by Health Canada to ensure that they are safe and effective before they can be offered to Canadians. To date, Health Canada has granted market authorization only for the stem cell therapy Prochymal to treat Graft versus Host Disease (GvHD), as well as two cell-based gene therapies, Kymriah and Yescarta , to treat certain cancers. However, most cell therapies are still experimental. This means that they may be administered to Canadians only if the health care practitioner is "
      ],
      [
        "Health Canada",
        "R_page_location\",\"allow_ad_personalization_signals\":false});gtag(\"config\", \"UA-21671527-4\", {\"groups\":\"default\",\"linker\":{\"domains\":[\"recalls-rappels.canada.ca\"]},\"page_placeholder\":\"PLACEHOLDER_page_path\",\"allow_ad_personalization_signals\":false}); Health Canada is advising Canadians about the potential health risks associated with unauthorized cell therapy treatments such as stem cell therapy - Canada.ca Skip to main content Skip to \"About government\" Language selection French fr Search Search Website Search You are here Canada.ca Health Recalls and safety alerts Recalls and safety alerts Information update Health Canada is advising Canadians about the potential health risks associated with unauthorized cell therapy treatments such as stem cell therapy Starting date: May 15, 2019 Type of communication: Information Update Subcategory: Drugs Source of recall: Health Canada Issue: Important Safety Information Audience: General Public, Healthcare Professionals Identification number: RA-69974 Last updated: 2019-05-15 Summary Who this is for: General Public Media enquiries Public enquiries OTTAWA – Health Canada is advising Canadians th"
      ],
      [
        "unauthorized",
        "27-4\", {\"groups\":\"default\",\"linker\":{\"domains\":[\"recalls-rappels.canada.ca\"]},\"page_placeholder\":\"PLACEHOLDER_page_path\",\"allow_ad_personalization_signals\":false}); Health Canada is advising Canadians about the potential health risks associated with unauthorized cell therapy treatments such as stem cell therapy - Canada.ca Skip to main content Skip to \"About government\" Language selection French fr Search Search Website Search You are here Canada.ca Health Recalls and safety alerts Recalls and safety alerts Information update Health Canada is advising Canadians about the potential health risks associated with unauthorized cell therapy treatments such as stem cell therapy Starting date: May 15, 2019 Type of communication: Information Update Subcategory: Drugs Source of recall: Health Canada Issue: Important Safety Information Audience: General Public, Healthcare Professionals Identification number: RA-69974 Last updated: 2019-05-15 Summary Who this is for: General Public Media enquiries Public enquiries OTTAWA – Health Canada is advising Canadians that some clinics and health care practitioners are offering unauthorized cell therapie"
      ],
      [
        "cell therapy",
        "ps\":\"default\",\"linker\":{\"domains\":[\"recalls-rappels.canada.ca\"]},\"page_placeholder\":\"PLACEHOLDER_page_path\",\"allow_ad_personalization_signals\":false}); Health Canada is advising Canadians about the potential health risks associated with unauthorized cell therapy treatments such as stem cell therapy - Canada.ca Skip to main content Skip to \"About government\" Language selection French fr Search Search Website Search You are here Canada.ca Health Recalls and safety alerts Recalls and safety alerts Information update Health Canada is advising Canadians about the potential health risks associated with unauthorized cell therapy treatments such as stem cell therapy Starting date: May 15, 2019 Type of communication: Information Update Subcategory: Drugs Source of recall: Health Canada Issue: Important Safety Information Audience: General Public, Healthcare Professionals Identification number: RA-69974 Last updated: 2019-05-15 Summary Who this is for: General Public Media enquiries Public enquiries OTTAWA – Health Canada is advising Canadians that some clinics and health care practitioners are offering unauthorized cell therapies, such as st"
      ]
    ]
  },
  "health_canada_policy": {
    "url": "https://www.canada.ca/en/health-canada/services/drugs-health-products/biologics-radiopharmaceuticals-genetic-therapies/applications-submissions/guidance-documents/cell-therapy-policy.html",
    "status": 200,
    "final": "https://www.canada.ca/en/health-canada/services/drugs-health-products/biologics-radiopharmaceuticals-genetic-therapies/applications-submissions/guidance-documents/cell-therapy-policy.html",
    "title": "Health Canada Policy Position Paper – Autologous Cell Therapy Products - Canada.ca",
    "snippets": [
      [
        "stem cells",
        "cessing activities and for a myriad of uses. Processing ranges from washing and cell separation to cell modification and expansion. Uses may vary from clinically proven application such as transplantation of minimally manipulated lymphohematopoietic stem cells to treat blood cancers within a hospital transplant centre, or Health Canada authorized investigations in clinical trials, to use of unauthorized and unproven therapies for the treatment of a myriad of disorders. However, it is the ability to use an individual’s biological material for their own therapeutic benefit that distinguishes autologous cell therapy products from allogeneic Footnote 2 cell therapy products. Because autologous cell therapy involves the use of a patient’s own cells, it can lead to assumptions that these therapies present minimal to no risk to recipients or that they would not be subject to the regulatory oversight given to drugs or other treatments. Some physicians may assume that autologous cell therapies are not governed by the Food and Drug Regulations – particularly when a cell therapy product involves less complicated processing steps, such as those"
      ],
      [
        "FDA",
        "asingly being used to process cells, including autologous cells, and some of these technologies have been classified as devices. International Regulatory Context: Other national regulatory authorities, such as the US Food and Drug Administration (US FDA) and the European Medicines Agency (EMA) have laws similar to Canada’s that allow them to regulate the distribution of cell therapy products in their respective jurisdictions. However, important differences exist. In particular, the European Union (EU) has enacted regulations specifically for cell therapy products, while the US FDA, like Health Canada, applies existing drug regulatory frameworks. Some national regulatory authorities have special exemptions for certain cell therapy products including those that are prepared at the bedside during the “same surgical procedure”, or “hospital exemptions” where all of the tissue processing and administration occurs within the same establishment. While a discussion on the regulatory challenges and benefits of these special exemptions is beyond the scope of this paper, it is important to note that no such exemptions exist in Canada. Position"
      ],
      [
        "serious adverse",
        ", and have the potential to persist in recipients for a prolonged period of time. This prolonged exposure, relative to the duration of exposure to most drugs, carries the potential for both long-term benefits and long-term risks. Indeed, a number of serious adverse events have been associated with use of autologous cell therapies and strategies to mitigate these risks are needed. The potential for harms associated with the use of cell therapies for which effectiveness has not been established, are also concerning. Therapeutic interventions pursued on the basis of anecdotal evidence that are ultimately proven ineffective or harmful when studied in well-controlled trials are common. The “new drug” sections c.08.002(1) and c.08.002(2)(g) of the FDR , together prohibit selling and advertising a drug where effectiveness has not been established. Claims that cell therapies are safe and effective must be based on evidence from well-controlled clinical studies. These requirements help prevent the use of unsafe or ineffective therapies, while permitting access to therapies with a favorable risk–benefit balance. 2. Accessing autologous cell t"
      ],
      [
        "patient",
        " among some stakeholders on how these products are regulated in Canada and in particular, how the present regulatory frameworks under the Food and Drugs Act (the Act ) can provide appropriate oversight of safety, efficacy and quality, while enabling patient access to potentially promising new therapies. This paper provides background on autologous cell therapy products, as well as the Canadian and International regulatory context. It addresses specific policy issues related to the regulation of autologous cell therapies, including: 1) The risks posed by autologous cell therapies; 2) The applicable federal product safety rules and how they can be complied with; and 3) The steps that are being taken by the regulator to assist in the development of these therapies. Background Autologous cell therapy involves the removal, some level of manipulation or processing, and re-introduction of a person’s own cells to treat or prevent a disease, disorder or medical condition. This may be done in a wide variety of settings (e.g. clinical setting, a hospital setting, or a more typical drug manufacturing setting) using a wide variety of processing "
      ],
      [
        "Health Canada",
        "Health Canada Policy Position Paper – Autologous Cell Therapy Products - Canada.ca !function(a){var e=\"https://s.go-mpulse.net/boomerang/\",t=\"addEventListener\";if(\"False\"==\"True\")a.BOOMR_config=a.BOOMR_config||{},a.BOOMR_config.PageParams=a.BOOMR_config.PageParams||{},a.BOOMR_config.PageParams.pci=!0,e=\"https://s2.go-mpulse.net/boomerang/\";if(window.BOOMR_API_key=\"KBFUZ-C9D7G-RB8SX-GRGEN-HGMC9\",function(){function n(e){a.BOOMR_onload=e&&e.timeStamp||(new Date).getTime()}if(!a.BOOMR||!a.BOOMR.version&&!a.BOOMR.snippetExecuted){a.BOOMR=a.BOOMR||{},a.BOOMR.snippetExecuted=!0;var i,_,o,r=document.createElement(\"iframe\");if(a[t])a[t](\"load\",n,!1);else if(a.attachEvent)a.attachEvent(\"onload\",n);r.src=\"javascript:void(0)\",r.title=\"\",r.role=\"presentation\",(r.frameElement||r).style.cssText=\"width:0;height:0;border:0;display:none;\",o=document.getElementsByTagName(\"script\")[0],o.parentNode.insertBe"
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        "unauthorized",
        "y from clinically proven application such as transplantation of minimally manipulated lymphohematopoietic stem cells to treat blood cancers within a hospital transplant centre, or Health Canada authorized investigations in clinical trials, to use of unauthorized and unproven therapies for the treatment of a myriad of disorders. However, it is the ability to use an individual’s biological material for their own therapeutic benefit that distinguishes autologous cell therapy products from allogeneic Footnote 2 cell therapy products. Because autologous cell therapy involves the use of a patient’s own cells, it can lead to assumptions that these therapies present minimal to no risk to recipients or that they would not be subject to the regulatory oversight given to drugs or other treatments. Some physicians may assume that autologous cell therapies are not governed by the Food and Drug Regulations – particularly when a cell therapy product involves less complicated processing steps, such as those prepared in a clinical setting using authorized medical devices. There is further uncertainty surrounding the practical means of meeting federa"
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  "stemregen_history": {
    "url": "https://www.stemregen.co/pages/history",
    "status": 200,
    "final": "https://www.stemregen.co/pages/history",
    "title": "History - Stemregen",
    "snippets": [
      [
        "Aphanizomenon",
        "px !important; }} Discovering the Power of AFA In the late 1990s, after obtaining his graduate degree in Neurophysiology from the Montreal Neurological Institute (affiliated with McGill University), Christian was hired to study the aquatic botanical Aphanizomenon flos-aquae (AFA) for its effect on the brain. He observed that consuming AFA led to significant health benefits, particularly in immune support, inflammation reduction, and mental clarity. These observations sparked an intense curiosity that would drive his research for years. Christian and his research team quickly identified that a polysaccharide from AFA supported various aspects of immunity, specifically the activity and migration capacity of natural killer (NK) cells. With its significant source of phycocyanin, they also found it reduced inflammatory responses and even helped with seemingly incurable conditions. They also discovered in their research that AFA contains phenylethylamine (PEA), a molecule that enhances dopaminergic nervous transmission, elevating mood and potentially benefiting individuals with Attention-Deficit Disorder (ADD). Despite these promising fin"
      ],
      [
        "stem cells",
        "things don't happen overnight. Over 20 years ago, STEMREGEN's founder, Christian Drapeau, began his journey to unravel the mysteries of the human body and its remarkable ability to heal. A pioneer of early stem cell research and the first to propose stem cells as the body's innate repair system, he would eventually transform our understanding of health and wellness into an entirely new paradigm. #shopify-section-template--25130864541974__section_qiYjHB .background-image-container {position: absolute; top: 0; right: 0; bottom: 0; left: auto; /* prevent stretching full width */ width: auto; height: auto; z-index: -1; opacity: var(--image-opacity, 1); pointer-events: none;} #shopify-section-template--25130864541974__section_qiYjHB .background-image-container img {display: block; width: 70vw; /* of viewport width */ max-width: 1200px; /* prevent it from getting too large */ height: auto; object-fit: contain; object-position: top right;} @media (max-width: 767px) {#shopify-section-template--25130864541974__section_qiYjHB .custom-font-size h2 {font-size: 37px !important; }} Discovering the Power of AFA In the late 1990s, after obtaining h"
      ],
      [
        "bone marrow",
        "hese promising findings, its known biochemistry could not explain many health benefits reported by people consuming AFA. It wasn't until the early 2000s that a breakthrough occurred in the scientific community, which was the first documentation that bone marrow stem cells have the ability to transform into various tissue types and effectively repair them. Fascinated by the finding, Christian and his colleague, Dr. Gitte Jensen, hypothesized that AFA might be acting as a natural stem cell mobilizer, increasing the number of circulating stem cells and enhancing the body's innate repair capabilities. Their research confirmed that AFA contains an L-selectin ligand that stimulates the release of stem cells from the bone marrow, increasing the number of circulating stem cells in the bloodstream by approximately 25%. This discovery had profound implications for regenerative medicine and prompted Christian to search for other natural ingredients with similar properties. The Quest for Stem Cell Mobilizers Christian set out to travel the world in search of plants historically known for their broad impact on health conditions. He spoke with me"
      ],
      [
        "FDA",
        " font-style: normal; font-display: swap; src: url(\"//www.stemregen.co/cdn/fonts/roboto/roboto_n3.9ac06d5955eb603264929711f38e40623ddc14db.woff2\") format(\"woff2\"), url(\"//www.stemregen.co/cdn/fonts/roboto/roboto_n3.797df4bf78042ba6106158fcf6a8d0e116fbfdae.woff\") format(\"woff\"); } @font-face { font-family: Roboto; font-weight: 700; font-style: normal; font-display: swap; src: url(\"//www.stemregen.co/cdn/fonts/roboto/roboto_n7.f38007a10afbbde8976c4056bfe890710d51dec2.woff2\") format(\"woff2\"), url(\"//www.stemregen.co/cdn/fonts/roboto/roboto_n7.94bfdd3e80c7be00e128703d245c207769d763f9.woff\") format(\"woff\"); } @font-face { font-family: Roboto; font-weight: 300; font-style: italic; font-display: swap; src: url(\"//www.stemregen.co/cdn/fonts/roboto/roboto_i3.7ba64865c0576ce320cbaa5e1e04a91d9daa2d3a.woff2\") format(\"woff2\"), url(\"//www.stemregen.co/cdn/fonts/roboto/roboto_i3.d974836b0cbb56a5fb4f6622c83b31968fe4c5d0.woff\") format(\"woff\"); } @font-face { font-family: Roboto; font-weight: 700; font-style: italic; font-display: swap; src: url(\"//www.stemregen.co/cdn/fonts/roboto/roboto_i7.7ccaf9410746f2c53340607c42c43f90a9005937.woff2\") format(\"wof"
      ],
      [
        "regenerative medicine",
        "ch confirmed that AFA contains an L-selectin ligand that stimulates the release of stem cells from the bone marrow, increasing the number of circulating stem cells in the bloodstream by approximately 25%. This discovery had profound implications for regenerative medicine and prompted Christian to search for other natural ingredients with similar properties. The Quest for Stem Cell Mobilizers Christian set out to travel the world in search of plants historically known for their broad impact on health conditions. He spoke with medicinal healers, shamans, biochemists, and others with intimate knowledge of local longevity remedies, which took him to remote regions like Madagascar and the Tibetan plateau. It was here that he discovered StemAloe® and SeaStem™ —a high-altitude sea buckthorn extract , both of which demonstrated a significant effect on stem cells. Christians' research uncovered that StemAloe , used by Malagasy people for centuries, stimulated stem cell release, increasing the number of circulating stem cells by upward of 80%. Similarly, SeaStem is known for its wide range of health benefits in Tibetan and Mongolian medicine,"
      ],
      [
        "extract",
        "ers, shamans, biochemists, and others with intimate knowledge of local longevity remedies, which took him to remote regions like Madagascar and the Tibetan plateau. It was here that he discovered StemAloe® and SeaStem™ —a high-altitude sea buckthorn extract , both of which demonstrated a significant effect on stem cells. Christians' research uncovered that StemAloe , used by Malagasy people for centuries, stimulated stem cell release, increasing the number of circulating stem cells by upward of 80%. Similarly, SeaStem is known for its wide range of health benefits in Tibetan and Mongolian medicine, which was shown to trigger the release of stem cells from the bone marrow, increasing by 35%. In 2016, after years of dedicated research and development, Christian introduced the first formulation supporting stem cell release, a unique proprietary blend of plant-based extracts documented to support Endogenous Stem Cell Mobilization (ESCM). This groundbreaking product marked the culmination of Christian's journey and the birth of his company, STEMREGEN. The Body's Innate Repair System To understand how the various STEMREGEN products work t"
      ]
    ]
  }
}