# Claim table — Youngover40 epigenome / monkey-wrinkle Reel

- **Facebook Reel source** — Confirmed: Share resolved to Facebook Reel 1535998168040564 from Youngover40. Public metadata/title says “Scientists just moved the clock backwards” and includes “a molecule injected into monkeys…” but does not name the molecule.
- **“A molecule injected into monkeys made wrinkles disappear.”** — Not verified in this check: The Reel gives no paper, molecule name, trial registration, animal species, dose or image/citation. Targeted PubMed/web searches did not recover a matching reliable primate wrinkle paper. Treat as an unsupported viral claim unless a paper is supplied.
- **Retinal cells can be made young again / vision restored.** — Real preclinical kernel, overstated for humans: Nature 2020 showed OSK partial reprogramming in mice promoted optic-nerve regeneration and restored vision in mouse glaucoma/aging models. This was not a monkey wrinkle study and not approved human age reversal.
- **DNA damage/epigenetic information theory explains aging.** — Hypothesis / research framework: Epigenetic changes are a real part of aging biology; the “corrupted software” metaphor comes from epigenetic-information-theory framing, not settled medical doctrine.
- **Exercise can “fix your epigenome.”** — Supported directionally, overstated: A 2026 systematic review/meta-analysis found higher physical activity is associated with lower epigenetic age by some DNA-methylation clocks, but evidence is largely observational/cross-sectional and does not prove exercise resets cells to youth.
- **No drugs or injections are needed; movement is useful.** — Health advice broadly supported, claim framing simplified: Regular physical activity is well-supported for health. It should not be sold as a guaranteed epigenetic age-reversal treatment.
- **NMN/NAD booster interpretation** — Possible adjacent topic, not shown in this Reel: The caption says “molecule” but transcript/contact-sheet do not name NMN. Existing NMN/NAD source-card remains relevant background, but this Reel cannot be attributed to NMN without more evidence.